FAQ
About Darvocet
Q)
What is Darvocet?
A) Structurally, it's a relative of the synthetic narcotic, methadone. It's prescribed
in two forms- propoxyphene hydrochloride and propoxyphene napsylate -for relief
of mild to moderate pain.
Aside
from slight differences-the napsylate (or N-form) of propoxyphene is more slowly
absorbed in the body and so has a longer duration of action-the two drugs are
identical. Both are found in a number of prescription pain medications, including:
- Darvon
and Darvon-N (propoxyphene only)
- Darvon
with A.S.A., Darvon-N with A.S.A. (with aspirin)
- Darvocet,
Darvocet-N, Wygesic (with acetaminophen)
- Darvon
Compound, Darvon Compound-65 (with aspirin and caffeine)
Q)
How is Darvocet used?
A)
Darvocet when abused is taken orally, chewed, crushed (then snorted like cocaine),
or crushed (then dissolved in water and injected like heroin).
Q)
What are the side effects of Darvocet?
A)
The side effects of Darvocet are:
- drowsiness
- dizziness
- nausea
- sedation
- vomiting
- abdominal
pain
- constipation
- feelings
of elation or depression
- hallucinations
- headache
- kidney
problems
- lightheadedness
- liver
problems
- minor
visual disturbances
- skin
rashes
- weakness
- yellowed
eyes and skin
Q)
What other medicines can interact with Darvocet?
A)
The propoxyphene in these drugs slows down the central nervous system and intensifies
the effects of alcohol. Heavy use of alcohol with this drug may cause overdose
symptoms. Therefore, limit or avoid use of alcohol while you are taking this medication.
If
these medications are taken with certain other drugs, the effects of either could
be increased, decreased, or altered. It is especially important to check with
your doctor before combining them with the following:
- Antiseizure
medications such as Tegretol
- Antidepressant
drugs such as Elavil
- Antihistamines
such as Benadryl
- Muscle
relaxants such as Flexeril
- Narcotic
pain relievers such as Demerol
- Sleep
aids such as Halcion
- Tranquilizers
such as Xanax and Valium
- Warfarin
-like drugs such as Coumadin
The
use of these drugs with propoxyphene can lead to potentially fatal overdose symptoms.
Severe
neurologic disorders, including coma, have occurred with the use of propoxyphene
in combination with Tegretol.
The
use of anticoagulants (blood thinners such as Coumadin) in combination with Darvon
Compound-65 may cause bleeding. If you are taking an anticoagulant, consult your
doctor before taking this drug.
The
use of aspirin with drugs for gout may alter the effects of the antigout medication.
Consult your doctor before taking Darvon Compound-65.
Q)
Is Darvocet addictive?
A)
Yes, given darvocet's similarities to methadone, it's not surprising that
the drug is as addictive as it is.
In
fact, the medical journal Clinical Pharmacology even argued that darvocet's "most
prominent effect...may be its addictive quality."
Darvon
produces psychological and physical dependence like other narcotics, and treatment
for Darvon dependence is much the same, too.
Q)
Can you overdose on Darvocet?
A)
Yes, the symptoms of an overdose are:
- Symptoms
of a propoxyphene overdose may include:
Bluish tinge to the skin, coma, convulsions,
decreased or difficult breathing to the point of temporary stoppage, decreased
heart function, extreme sleepiness, irregular heartbeat, low blood pressure, pinpoint
pupils becoming dilated later, stupor
- Additional
symptoms of overdose with Darvocet-N:
Abdominal pain, excessive sweating,
general feeling of illness, kidney failure, liver problems, loss of appetite,
nausea, vomiting
- Additional
symptoms of overdose with Darvon Compound-65:
Confusion, deafness, excessive
perspiration, headache, mental dullness, nausea, rapid breathing, rapid pulse,
ringing in the ears, vertigo, vomiting
Extreme
overdose may lead to unconsciousness and death.
Special
information if you are pregnant or breastfeeding
Do
not take these medications if you are pregnant or planning to become pregnant
unless you are directed to do so by your doctor. Temporary drug dependence may
occur in newborns when the mother has taken this drug consistently in the weeks
before delivery. The use of Darvon Compound-65 (which contains aspirin) during
pregnancy may cause problems in the developing baby or complications during delivery.
Do not take it during the last 3 months of pregnancy. Darvocet-N does appear in
breast milk.
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